DES protein (Cavia aperea) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

DES

Desmin. (277 aa)

Predicted Functional Partners:

GFAP

0.993

SYNC

0.973

ENSCAPP00000006340

0.959

GAN

0.934

SYNM

0.914

NOD2

0.902

PLEC

0.873

ENSCAPP00000002343

0.848

ENSCAPP00000008125

0.848

PPL

0.848

Your Current Organism:

Cavia aperea

NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea

Export your current network:

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same PNG format, but at higher resolution

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SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

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TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DES	ENSCAPP00000002343	ENSCAPP00000004465	ENSCAPP00000002343	Desmin.	annotation not available	0.848
DES	ENSCAPP00000006340	ENSCAPP00000004465	ENSCAPP00000006340	Desmin.	annotation not available	0.959
DES	ENSCAPP00000008125	ENSCAPP00000004465	ENSCAPP00000008125	Desmin.	annotation not available	0.848
DES	GAN	ENSCAPP00000004465	ENSCAPP00000010300	Desmin.	Gigaxonin.	0.934
DES	GFAP	ENSCAPP00000004465	ENSCAPP00000015295	Desmin.	Glial fibrillary acidic protein.	0.993
DES	NOD2	ENSCAPP00000004465	ENSCAPP00000017799	Desmin.	Nucleotide binding oligomerization domain containing 2.	0.902
DES	PLEC	ENSCAPP00000004465	ENSCAPP00000012984	Desmin.	Plectin.	0.873
DES	PPL	ENSCAPP00000004465	ENSCAPP00000014519	Desmin.	Periplakin.	0.848
DES	SYNC	ENSCAPP00000004465	ENSCAPP00000012220	Desmin.	Syncoilin, intermediate filament protein.	0.973
DES	SYNM	ENSCAPP00000004465	ENSCAPP00000000400	Desmin.	Synemin.	0.914
ENSCAPP00000002343	DES	ENSCAPP00000002343	ENSCAPP00000004465	annotation not available	Desmin.	0.848
ENSCAPP00000002343	ENSCAPP00000006340	ENSCAPP00000002343	ENSCAPP00000006340	annotation not available	annotation not available	0.957
ENSCAPP00000002343	GFAP	ENSCAPP00000002343	ENSCAPP00000015295	annotation not available	Glial fibrillary acidic protein.	0.457
ENSCAPP00000002343	PLEC	ENSCAPP00000002343	ENSCAPP00000012984	annotation not available	Plectin.	0.845
ENSCAPP00000006340	DES	ENSCAPP00000006340	ENSCAPP00000004465	annotation not available	Desmin.	0.959
ENSCAPP00000006340	ENSCAPP00000002343	ENSCAPP00000006340	ENSCAPP00000002343	annotation not available	annotation not available	0.957
ENSCAPP00000006340	ENSCAPP00000008125	ENSCAPP00000006340	ENSCAPP00000008125	annotation not available	annotation not available	0.957
ENSCAPP00000006340	PLEC	ENSCAPP00000006340	ENSCAPP00000012984	annotation not available	Plectin.	0.665
ENSCAPP00000008125	DES	ENSCAPP00000008125	ENSCAPP00000004465	annotation not available	Desmin.	0.848
ENSCAPP00000008125	ENSCAPP00000006340	ENSCAPP00000008125	ENSCAPP00000006340	annotation not available	annotation not available	0.957