Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DNMT3ADNA methyltransferase 3 alpha. (907 aa)    
Predicted Functional Partners:
DNMT1
DNA methyltransferase 1.
   
 0.999
ENSCAPP00000018273
annotation not available
    
 0.999
EZH2
Enhancer of zeste 2 polycomb repressive complex 2 subunit.
   
 0.982
UHRF1
Ubiquitin like with PHD and ring finger domains 1.
    
 
 0.969
HDAC1
Histone deacetylase 1.
    
 
 0.960
ENSCAPP00000001550
annotation not available
    
 0.956
ENSCAPP00000002246
annotation not available
   
 
 0.955
ENSCAPP00000015867
annotation not available
   
 
 0.927
AHCY
Adenosylhomocysteinase.
     
 0.917
MAT2A
Methionine adenosyltransferase 2A.
     
 0.916
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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