BIN1 protein (Cavia aperea) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

BIN1

Bridging integrator 1. (581 aa)

Predicted Functional Partners:

MYC

0.997

ENSCAPP00000002126

0.996

AMPH

0.996

DNM1

0.994

ENSCAPP00000012429

0.970

ENSCAPP00000013227

0.966

CLU

0.966

ENSCAPP00000016724

0.956

ENSCAPP00000017019

0.956

BIN3

0.949

Your Current Organism:

Cavia aperea

NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea

Export your current network:

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file format is 'PNG': portable network graphic

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same PNG format, but at higher resolution

... as a vector graphic:

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SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

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TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AMPH	BIN1	ENSCAPP00000003935	ENSCAPP00000004497	Amphiphysin.	Bridging integrator 1.	0.996
AMPH	BIN3	ENSCAPP00000003935	ENSCAPP00000008562	Amphiphysin.	Bridging integrator 3.	0.655
AMPH	CLU	ENSCAPP00000003935	ENSCAPP00000015388	Amphiphysin.	Clusterin.	0.838
AMPH	DNM1	ENSCAPP00000003935	ENSCAPP00000014787	Amphiphysin.	Dynamin 1.	0.997
AMPH	ENSCAPP00000002126	ENSCAPP00000003935	ENSCAPP00000002126	Amphiphysin.	annotation not available	0.998
AMPH	ENSCAPP00000012429	ENSCAPP00000003935	ENSCAPP00000012429	Amphiphysin.	annotation not available	0.874
AMPH	ENSCAPP00000013227	ENSCAPP00000003935	ENSCAPP00000013227	Amphiphysin.	annotation not available	0.965
AMPH	ENSCAPP00000016724	ENSCAPP00000003935	ENSCAPP00000016724	Amphiphysin.	annotation not available	0.780
AMPH	ENSCAPP00000017019	ENSCAPP00000003935	ENSCAPP00000017019	Amphiphysin.	annotation not available	0.780
AMPH	MYC	ENSCAPP00000003935	ENSCAPP00000005163	Amphiphysin.	MYC proto-oncogene, bHLH transcription factor.	0.963
BIN1	AMPH	ENSCAPP00000004497	ENSCAPP00000003935	Bridging integrator 1.	Amphiphysin.	0.996
BIN1	BIN3	ENSCAPP00000004497	ENSCAPP00000008562	Bridging integrator 1.	Bridging integrator 3.	0.949
BIN1	CLU	ENSCAPP00000004497	ENSCAPP00000015388	Bridging integrator 1.	Clusterin.	0.966
BIN1	DNM1	ENSCAPP00000004497	ENSCAPP00000014787	Bridging integrator 1.	Dynamin 1.	0.994
BIN1	ENSCAPP00000002126	ENSCAPP00000004497	ENSCAPP00000002126	Bridging integrator 1.	annotation not available	0.996
BIN1	ENSCAPP00000012429	ENSCAPP00000004497	ENSCAPP00000012429	Bridging integrator 1.	annotation not available	0.970
BIN1	ENSCAPP00000013227	ENSCAPP00000004497	ENSCAPP00000013227	Bridging integrator 1.	annotation not available	0.966
BIN1	ENSCAPP00000016724	ENSCAPP00000004497	ENSCAPP00000016724	Bridging integrator 1.	annotation not available	0.956
BIN1	ENSCAPP00000017019	ENSCAPP00000004497	ENSCAPP00000017019	Bridging integrator 1.	annotation not available	0.956
BIN1	MYC	ENSCAPP00000004497	ENSCAPP00000005163	Bridging integrator 1.	MYC proto-oncogene, bHLH transcription factor.	0.997