STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HHIPHedgehog interacting protein. (626 aa)    
Predicted Functional Partners:
IHH
Indian hedgehog signaling molecule.
    
 0.997
GLI1
GLI family zinc finger 1.
    
 
 0.815
PTCH1
Patched 1.
    
 
 0.812
SH3GL3
SH3 domain containing GRB2 like 3, endophilin A3.
    
 
 0.787
DYM
Dymeclin.
      
 0.785
GLI2
GLI family zinc finger 2.
    
 
 0.758
SORL1
Sortilin related receptor 1.
    
 0.757
USP38
Ubiquitin specific peptidase 38.
      
 0.742
NRP1
Neuropilin 1.
    
 
 0.692
BCKDHB
Branched chain keto acid dehydrogenase E1 subunit beta.
      
 0.692
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.