STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HHIPHedgehog interacting protein. (626 aa)    
Predicted Functional Partners:
IHH
Indian hedgehog signaling molecule.
    
 0.991
SORL1
Sortilin related receptor 1.
    
 0.879
PTCH1
Patched 1.
    
 
 0.657
SH3GL3
SH3 domain containing GRB2 like 3, endophilin A3.
    
 
 0.602
F2R
Coagulation factor II thrombin receptor.
    
 0.599
SMO
Smoothened, frizzled class receptor.
    
 
 0.581
NCSTN
Nicastrin.
    
 0.567
ENSCAPP00000005147
annotation not available
    
 0.562
HABP2
Hyaluronan binding protein 2.
    
 0.562
HGFAC
HGF activator.
    
 0.562
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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