Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADAM23ADAM metallopeptidase domain 23. (761 aa)    
Predicted Functional Partners:
LGI2
Leucine rich repeat LGI family member 2.
     
 0.974
ENSCAPP00000005227
annotation not available
   
 0.913
ADAM22
ADAM metallopeptidase domain 22.
   
 0.861
LGI3
Leucine rich repeat LGI family member 3.
   
 
 0.806
ADAM11
ADAM metallopeptidase domain 11.
   
 0.747
LGI4
Leucine rich repeat LGI family member 4.
     
 0.724
STX6
Syntaxin 6.
      
 0.654
PRDM5
PR/SET domain 5.
      
 0.623
SENP6
SUMO specific peptidase 6.
    
   0.613
KANSL3
KAT8 regulatory NSL complex subunit 3.
      
 0.602
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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