STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TRIB3Tribbles pseudokinase 3. (353 aa)    
Predicted Functional Partners:
AKT1
AKT serine/threonine kinase 1.
    
 0.998
ATF4
Activating transcription factor 4.
   
 0.983
AKT3
AKT serine/threonine kinase 3.
    
 0.981
AKT2
AKT serine/threonine kinase 2.
    
 0.981
COP1
COP1 E3 ubiquitin ligase.
    
 
 0.963
STK40
Serine/threonine kinase 40.
    
 
 0.961
CHAC1
ChaC glutathione specific gamma-glutamylcyclotransferase 1.
   
 
 0.946
PPARA
Peroxisome proliferator activated receptor alpha.
    
 0.931
SQSTM1
Sequestosome 1.
    
 
 0.926
APPL2
Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2.
    
  0.889
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.