OTULIN protein (Cavia aperea) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

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Textmining

[Homology]

Score

OTULIN

OTU deubiquitinase with linear linkage specificity. (328 aa)

Predicted Functional Partners:

RBCK1

0.998

ENSCAPP00000015425

0.998

SNX27

0.965

TNF

0.961

UBA52

0.926

ENSCAPP00000010366

0.926

ENSCAPP00000000492

0.907

ENSCAPP00000004155

0.907

ENSCAPP00000014462

0.907

OTUD7B

0.892

Your Current Organism:

Cavia aperea

NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSCAPP00000000492	ENSCAPP00000010366	ENSCAPP00000000492	ENSCAPP00000010366	annotation not available	annotation not available	0.991
ENSCAPP00000000492	ENSCAPP00000015425	ENSCAPP00000000492	ENSCAPP00000015425	annotation not available	annotation not available	0.896
ENSCAPP00000000492	OTUD7B	ENSCAPP00000000492	ENSCAPP00000000504	annotation not available	OTU deubiquitinase 7B.	0.884
ENSCAPP00000000492	OTULIN	ENSCAPP00000000492	ENSCAPP00000004605	annotation not available	OTU deubiquitinase with linear linkage specificity.	0.907
ENSCAPP00000000492	RBCK1	ENSCAPP00000000492	ENSCAPP00000001534	annotation not available	RANBP2-type and C3HC4-type zinc finger containing 1.	0.879
ENSCAPP00000000492	TNF	ENSCAPP00000000492	ENSCAPP00000013893	annotation not available	Tumor necrosis factor.	0.526
ENSCAPP00000000492	UBA52	ENSCAPP00000000492	ENSCAPP00000005037	annotation not available	Ubiquitin A-52 residue ribosomal protein fusion product 1.	0.991
ENSCAPP00000004155	ENSCAPP00000010366	ENSCAPP00000004155	ENSCAPP00000010366	annotation not available	annotation not available	0.991
ENSCAPP00000004155	ENSCAPP00000015425	ENSCAPP00000004155	ENSCAPP00000015425	annotation not available	annotation not available	0.896
ENSCAPP00000004155	OTUD7B	ENSCAPP00000004155	ENSCAPP00000000504	annotation not available	OTU deubiquitinase 7B.	0.884
ENSCAPP00000004155	OTULIN	ENSCAPP00000004155	ENSCAPP00000004605	annotation not available	OTU deubiquitinase with linear linkage specificity.	0.907
ENSCAPP00000004155	RBCK1	ENSCAPP00000004155	ENSCAPP00000001534	annotation not available	RANBP2-type and C3HC4-type zinc finger containing 1.	0.879
ENSCAPP00000004155	TNF	ENSCAPP00000004155	ENSCAPP00000013893	annotation not available	Tumor necrosis factor.	0.526
ENSCAPP00000004155	UBA52	ENSCAPP00000004155	ENSCAPP00000005037	annotation not available	Ubiquitin A-52 residue ribosomal protein fusion product 1.	0.991
ENSCAPP00000010366	ENSCAPP00000000492	ENSCAPP00000010366	ENSCAPP00000000492	annotation not available	annotation not available	0.991
ENSCAPP00000010366	ENSCAPP00000004155	ENSCAPP00000010366	ENSCAPP00000004155	annotation not available	annotation not available	0.991
ENSCAPP00000010366	ENSCAPP00000014462	ENSCAPP00000010366	ENSCAPP00000014462	annotation not available	annotation not available	0.993
ENSCAPP00000010366	ENSCAPP00000015425	ENSCAPP00000010366	ENSCAPP00000015425	annotation not available	annotation not available	0.910
ENSCAPP00000010366	OTUD7B	ENSCAPP00000010366	ENSCAPP00000000504	annotation not available	OTU deubiquitinase 7B.	0.900
ENSCAPP00000010366	OTULIN	ENSCAPP00000010366	ENSCAPP00000004605	annotation not available	OTU deubiquitinase with linear linkage specificity.	0.926