Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
USP25Ubiquitin specific peptidase 25. (952 aa)    
Predicted Functional Partners:
SYK
Spleen associated tyrosine kinase.
    
  0.967
KCTD13
Potassium channel tetramerization domain containing 13.
    
 
 0.959
KCTD10
Potassium channel tetramerization domain containing 10.
    
 
 0.959
TRAF6
TNF receptor associated factor 6.
    
 0.944
ENSCAPP00000013239
annotation not available
    
 0.942
TNFAIP1
TNF alpha induced protein 1.
    
 
 0.935
TRIP12
Thyroid hormone receptor interactor 12.
   
 
 0.928
DDX58
DExD/H-box helicase 58.
   
 
 0.927
MYC
MYC proto-oncogene, bHLH transcription factor.
    
 0.926
TNKS
Tankyrase.
    
 0.923
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.