Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
FADS1Fatty acid desaturase 1. (429 aa)    
Predicted Functional Partners:
ELOVL5
ELOVL fatty acid elongase 5.
   
 
 0.939
ELOVL2
ELOVL fatty acid elongase 2.
     
 0.935
TECR
trans-2,3-enoyl-CoA reductase.
     
 0.876
HSD17B12
Hydroxysteroid 17-beta dehydrogenase 12.
    
 0.870
HACD3
3-hydroxyacyl-CoA dehydratase 3.
     
 0.868
HACD2
3-hydroxyacyl-CoA dehydratase 2.
     
 0.863
HACD4
3-hydroxyacyl-CoA dehydratase 4.
     
  0.861
PLA2G4A
Phospholipase A2 group IVA.
     
 0.844
PLAAT3
Phospholipase A and acyltransferase 3.
     
 0.840
PLA2G2E
Phospholipase A2 group IIE.
     
  0.839
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
Server load: low (20%) [HD]