STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CRADDCASP2 and RIPK1 domain containing adaptor with death domain. (199 aa)    
Predicted Functional Partners:
PIDD1
P53-induced death domain protein 1.
    
 0.999
CASP2
Caspase 2.
    
 0.994
ENSCAPP00000012201
annotation not available
   
    0.974
LUM
Lumican.
    
 0.912
THOP1
Thimet oligopeptidase 1.
      
 0.894
HTR5A
5-hydroxytryptamine receptor 5A.
      
 0.887
ENSCAPP00000009470
annotation not available
      
 0.881
NEDD9
Neural precursor cell expressed, developmentally down-regulated 9.
      
 0.875
PTPRG
Protein tyrosine phosphatase receptor type G.
      
 0.872
GRIN3A
Glutamate ionotropic receptor NMDA type subunit 3A.
      
 0.865
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.