Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DSG1Desmoglein 1. (978 aa)    
Predicted Functional Partners:
PKP1
Plakophilin 1.
   
 0.998
JUP
Junction plakoglobin.
    
 0.995
ENSCAPP00000013192
annotation not available
   
 0.994
PKP2
Plakophilin 2.
   
 0.982
DSC1
Desmocollin 1.
   
 0.971
DSC2
Desmocollin 2.
   
 0.966
DSC3
Desmocollin 3.
   
 0.966
PLEC
Plectin.
   
 0.957
CASP14
Caspase 14.
   
 0.939
KRT79
Keratin 79.
  
 0.936
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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