STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PERPP53 apoptosis effector related to PMP22. (121 aa)    
Predicted Functional Partners:
PKP1
Plakophilin 1.
   
 
 0.757
PKP3
Plakophilin 3.
   
 
 0.755
PKP2
Plakophilin 2.
   
 
 0.688
TP53
Tumor protein p53.
    
 0.660
ENSCAPP00000013192
annotation not available
   
 
 0.653
JUP
Junction plakoglobin.
     
 0.629
ENSCAPP00000007736
annotation not available
    
 0.629
ENSCAPP00000005516
annotation not available
     
 0.611
PKP4
Plakophilin 4.
     
 0.611
DSG1
Desmoglein 1.
     
 0.590
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.