Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PCPyruvate carboxylase. (1160 aa)    
Predicted Functional Partners:
PKM
Pyruvate kinase M1/2.
    
 0.983
ME1
Malic enzyme 1.
   
 0.982
PCK1
Phosphoenolpyruvate carboxykinase 1.
  
 
 0.976
PKLR
Pyruvate kinase L/R.
    
 0.976
CS
Citrate synthase.
  
 
 0.974
MDH2
Malate dehydrogenase 2.
  
 0.971
ME3
Malic enzyme 3.
   
 0.971
LDHA
Lactate dehydrogenase A.
  
 0.971
PCK2
Phosphoenolpyruvate carboxykinase 2, mitochondrial.
  
 
 0.964
ENSCAPP00000000130
annotation not available
   
 0.962
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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