STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HIC2HIC ZBTB transcriptional repressor 2. (542 aa)    
Predicted Functional Partners:
SIRT1
Sirtuin 1.
    
 0.659
KDM6B
Lysine demethylase 6B.
  
 
 0.656
SUMO1
Small ubiquitin like modifier 1.
    
  0.642
ENSCAPP00000015419
annotation not available
    
 
 0.586
ENSCAPP00000005571
annotation not available
    
 0.568
MYSM1
Myb like, SWIRM and MPN domains 1.
    
 0.562
ENSCAPP00000013045
annotation not available
    
  0.544
BARD1
BRCA1 associated RING domain 1.
    
 0.542
MRPS11
Mitochondrial ribosomal protein S11.
    
  0.539
MRPS6
Mitochondrial ribosomal protein S6.
    
  0.536
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.