Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SIK3SIK family kinase 3. (1251 aa)    
Predicted Functional Partners:
YWHAZ
Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta.
    
 0.962
CRTC2
CREB regulated transcription coactivator 2.
    
 0.918
CRTC3
CREB regulated transcription coactivator 3.
    
 0.889
PPP3CA
Protein phosphatase 3 catalytic subunit alpha.
    
 0.842
ENSCAPP00000009903
annotation not available
    
 0.836
ENSCAPP00000017737
annotation not available
    
 0.836
PPP3CC
Protein phosphatase 3 catalytic subunit gamma.
    
 0.816
TSHR
Thyroid stimulating hormone receptor.
     
 0.766
THRA
Thyroid hormone receptor alpha.
    
 
 0.686
GINS4
GINS complex subunit 4.
    
   0.669
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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