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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RETSATRetinol saturase. (553 aa)    
Predicted Functional Partners:
FDFT1
Farnesyl-diphosphate farnesyltransferase 1.
  
 
 0.961
NDUFAF6
NADH:ubiquinone oxidoreductase complex assembly factor 6.
  
 
 0.954
DHRS3
Dehydrogenase/reductase 3.
    
 0.922
ENSCAPP00000010601
annotation not available
    
 0.920
RDH12
Retinol dehydrogenase 12.
    
 0.920
ENSCAPP00000007271
annotation not available
  
 
 0.916
SDR16C5
Short chain dehydrogenase/reductase family 16C member 5.
    
 0.912
RDH8
Retinol dehydrogenase 8.
    
 0.912
ENSCAPP00000007406
annotation not available
     
 0.907
DHRS9
Dehydrogenase/reductase 9.
     
 0.907
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.