STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EGFEpidermal growth factor. (1120 aa)    
Predicted Functional Partners:
EGFR
Epidermal growth factor receptor.
   
 0.998
ERBB3
Erb-b2 receptor tyrosine kinase 3.
   
 0.965
ERBB2
Erb-b2 receptor tyrosine kinase 2.
   
 0.965
ENSCAPP00000009690
annotation not available
   
 0.938
ENSCAPP00000010272
annotation not available
   
 0.938
NTRK1
Neurotrophic receptor tyrosine kinase 1.
   
 0.920
IGF1R
Insulin like growth factor 1 receptor.
    
 0.912
TGFA
Transforming growth factor alpha.
     
0.909
INS
Insulin.
     
 0.909
HGF
Hepatocyte growth factor.
     
 0.905
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.