Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
FCHO2FCH and mu domain containing endocytic adaptor 2. (506 aa)    
Predicted Functional Partners:
ITSN2
Intersectin 2.
   
 0.972
EPS15
Epidermal growth factor receptor pathway substrate 15.
    
 0.965
AP2S1
Adaptor related protein complex 2 subunit sigma 1.
    
 0.963
AP2B1
Adaptor related protein complex 2 subunit beta 1.
    
 0.949
ENSCAPP00000013876
annotation not available
   
 0.925
EPS15L1
Epidermal growth factor receptor pathway substrate 15 like 1.
    
 0.924
ENSCAPP00000011420
annotation not available
   
 0.917
ITSN1
Intersectin 1.
    
 0.883
ENSCAPP00000013032
annotation not available
    
 0.883
AP2A1
Adaptor related protein complex 2 subunit alpha 1.
    
 0.866
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
Server load: low (10%) [HD]