Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RNF222Ring finger protein 222. (215 aa)    
Predicted Functional Partners:
SEZ6L
Seizure related 6 homolog like.
      
 0.573
PI15
Peptidase inhibitor 15.
      
 0.475
MUC15
Mucin 15, cell surface associated.
      
 0.454
GABRP
Gamma-aminobutyric acid type A receptor pi subunit.
      
 0.440
GABRD
Gamma-aminobutyric acid type A receptor delta subunit.
      
 0.428
BACE2
Beta-secretase 2.
      
 0.408
SSTR3
Somatostatin receptor 3.
  
     0.400
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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