Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AGFG2ArfGAP with FG repeats 2. (382 aa)    
Predicted Functional Partners:
ACAP1
ArfGAP with coiled-coil, ankyrin repeat and PH domains 1.
      
 0.943
EPS15L1
Epidermal growth factor receptor pathway substrate 15 like 1.
    
 0.871
EPS15
Epidermal growth factor receptor pathway substrate 15.
    
 0.792
LRCH4
Leucine rich repeats and calponin homology domain containing 4.
      
 0.745
ASAP2
ArfGAP with SH3 domain, ankyrin repeat and PH domain 2.
      
 0.743
ITSN2
Intersectin 2.
    
 0.738
ARAP3
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3.
      
 0.692
ANKRD46
Ankyrin repeat domain 46.
      
 0.690
GNB2
G protein subunit beta 2.
      
 0.683
ARAP2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2.
      
 0.674
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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