Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PXNPaxillin. (424 aa)    
Predicted Functional Partners:
ENSCAPP00000013002
annotation not available
    
 0.997
VCL
Vinculin.
    
 0.995
BCAR1
BCAR1 scaffold protein, Cas family member.
    
 0.994
CRK
CRK proto-oncogene, adaptor protein.
    
 0.992
PTK2B
Protein tyrosine kinase 2 beta.
    
 0.991
GIT1
GIT ArfGAP 1.
    
 0.990
ILK
Integrin linked kinase.
   
 0.989
PARVA
Parvin alpha.
    
 0.987
ITGB1
Integrin subunit beta 1.
    
 0.986
TLN1
Talin 1.
   
 0.983
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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