PROKR1 protein (Cavia aperea) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

PROKR1

Prokineticin receptor 1. (393 aa)

Predicted Functional Partners:

PROK1

0.728

ENSCAPP00000000375

0.712

EDN1

0.701

GNAQ

0.592

GNA14

0.592

GNA11

0.592

ENSCAPP00000005162

0.588

F2

0.582

AGT

0.570

GRK3

0.554

Your Current Organism:

Cavia aperea

NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AGT	EDN1	ENSCAPP00000008025	ENSCAPP00000016242	Angiotensinogen.	Endothelin 1.	0.766
AGT	ENSCAPP00000000375	ENSCAPP00000008025	ENSCAPP00000000375	Angiotensinogen.	annotation not available	0.544
AGT	F2	ENSCAPP00000008025	ENSCAPP00000013583	Angiotensinogen.	Coagulation factor II, thrombin.	0.737
AGT	GNA11	ENSCAPP00000008025	ENSCAPP00000006073	Angiotensinogen.	G protein subunit alpha 11.	0.584
AGT	GNA14	ENSCAPP00000008025	ENSCAPP00000005868	Angiotensinogen.	G protein subunit alpha 14.	0.538
AGT	GNAQ	ENSCAPP00000008025	ENSCAPP00000002258	Angiotensinogen.	G protein subunit alpha q.	0.584
AGT	GRK3	ENSCAPP00000008025	ENSCAPP00000002976	Angiotensinogen.	G protein-coupled receptor kinase 3.	0.476
AGT	PROKR1	ENSCAPP00000008025	ENSCAPP00000004914	Angiotensinogen.	Prokineticin receptor 1.	0.570
EDN1	AGT	ENSCAPP00000016242	ENSCAPP00000008025	Endothelin 1.	Angiotensinogen.	0.766
EDN1	ENSCAPP00000000375	ENSCAPP00000016242	ENSCAPP00000000375	Endothelin 1.	annotation not available	0.849
EDN1	ENSCAPP00000005162	ENSCAPP00000016242	ENSCAPP00000005162	Endothelin 1.	annotation not available	0.484
EDN1	F2	ENSCAPP00000016242	ENSCAPP00000013583	Endothelin 1.	Coagulation factor II, thrombin.	0.646
EDN1	GNA11	ENSCAPP00000016242	ENSCAPP00000006073	Endothelin 1.	G protein subunit alpha 11.	0.521
EDN1	GNA14	ENSCAPP00000016242	ENSCAPP00000005868	Endothelin 1.	G protein subunit alpha 14.	0.496
EDN1	GNAQ	ENSCAPP00000016242	ENSCAPP00000002258	Endothelin 1.	G protein subunit alpha q.	0.521
EDN1	GRK3	ENSCAPP00000016242	ENSCAPP00000002976	Endothelin 1.	G protein-coupled receptor kinase 3.	0.547
EDN1	PROK1	ENSCAPP00000016242	ENSCAPP00000004341	Endothelin 1.	Prokineticin 1.	0.509
EDN1	PROKR1	ENSCAPP00000016242	ENSCAPP00000004914	Endothelin 1.	Prokineticin receptor 1.	0.701
ENSCAPP00000000375	AGT	ENSCAPP00000000375	ENSCAPP00000008025	annotation not available	Angiotensinogen.	0.544
ENSCAPP00000000375	EDN1	ENSCAPP00000000375	ENSCAPP00000016242	annotation not available	Endothelin 1.	0.849