CHAF1A protein (Cavia aperea) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

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Gene Fusion

Co-occurrence

Co-expression

Experiments

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[Homology]

Score

CHAF1A

Chromatin assembly factor 1 subunit A. (827 aa)

Predicted Functional Partners:

CHAF1B

0.999

ASF1A

0.987

ASF1B

0.980

PCNA

0.978

ENSCAPP00000002246

0.962

ENSCAPP00000001714

0.958

ENSCAPP00000004252

0.958

ENSCAPP00000006354

0.958

ENSCAPP00000015067

0.958

CBX1

0.936

Your Current Organism:

Cavia aperea

NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ASF1A	ASF1B	ENSCAPP00000005345	ENSCAPP00000004210	Anti-silencing function 1A histone chaperone.	Anti-silencing function 1B histone chaperone.	0.965
ASF1A	CHAF1A	ENSCAPP00000005345	ENSCAPP00000004926	Anti-silencing function 1A histone chaperone.	Chromatin assembly factor 1 subunit A.	0.987
ASF1A	CHAF1B	ENSCAPP00000005345	ENSCAPP00000017079	Anti-silencing function 1A histone chaperone.	Chromatin assembly factor 1 subunit B.	0.968
ASF1A	ENSCAPP00000001714	ENSCAPP00000005345	ENSCAPP00000001714	Anti-silencing function 1A histone chaperone.	annotation not available	0.846
ASF1A	ENSCAPP00000004252	ENSCAPP00000005345	ENSCAPP00000004252	Anti-silencing function 1A histone chaperone.	annotation not available	0.846
ASF1A	ENSCAPP00000006354	ENSCAPP00000005345	ENSCAPP00000006354	Anti-silencing function 1A histone chaperone.	annotation not available	0.846
ASF1A	ENSCAPP00000015067	ENSCAPP00000005345	ENSCAPP00000015067	Anti-silencing function 1A histone chaperone.	annotation not available	0.846
ASF1A	PCNA	ENSCAPP00000005345	ENSCAPP00000014064	Anti-silencing function 1A histone chaperone.	Proliferating cell nuclear antigen.	0.823
ASF1B	ASF1A	ENSCAPP00000004210	ENSCAPP00000005345	Anti-silencing function 1B histone chaperone.	Anti-silencing function 1A histone chaperone.	0.965
ASF1B	CHAF1A	ENSCAPP00000004210	ENSCAPP00000004926	Anti-silencing function 1B histone chaperone.	Chromatin assembly factor 1 subunit A.	0.980
ASF1B	CHAF1B	ENSCAPP00000004210	ENSCAPP00000017079	Anti-silencing function 1B histone chaperone.	Chromatin assembly factor 1 subunit B.	0.979
ASF1B	ENSCAPP00000001714	ENSCAPP00000004210	ENSCAPP00000001714	Anti-silencing function 1B histone chaperone.	annotation not available	0.708
ASF1B	ENSCAPP00000004252	ENSCAPP00000004210	ENSCAPP00000004252	Anti-silencing function 1B histone chaperone.	annotation not available	0.708
ASF1B	ENSCAPP00000006354	ENSCAPP00000004210	ENSCAPP00000006354	Anti-silencing function 1B histone chaperone.	annotation not available	0.708
ASF1B	ENSCAPP00000015067	ENSCAPP00000004210	ENSCAPP00000015067	Anti-silencing function 1B histone chaperone.	annotation not available	0.708
ASF1B	PCNA	ENSCAPP00000004210	ENSCAPP00000014064	Anti-silencing function 1B histone chaperone.	Proliferating cell nuclear antigen.	0.823
CBX1	CHAF1A	ENSCAPP00000001875	ENSCAPP00000004926	Chromobox 1.	Chromatin assembly factor 1 subunit A.	0.936
CBX1	CHAF1B	ENSCAPP00000001875	ENSCAPP00000017079	Chromobox 1.	Chromatin assembly factor 1 subunit B.	0.896
CBX1	ENSCAPP00000001714	ENSCAPP00000001875	ENSCAPP00000001714	Chromobox 1.	annotation not available	0.678
CBX1	ENSCAPP00000002246	ENSCAPP00000001875	ENSCAPP00000002246	Chromobox 1.	annotation not available	0.971