Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSCAPP00000004927annotation not available (202 aa)    
Predicted Functional Partners:
NLRP3
NLR family pyrin domain containing 3.
    
 0.997
ENSCAPP00000006417
annotation not available
    
 0.989
ENSCAPP00000009620
annotation not available
    
 0.989
ENSCAPP00000010372
annotation not available
    
 0.989
WWP1
WW domain containing E3 ubiquitin protein ligase 1.
    
 
 0.961
ITCH
Itchy E3 ubiquitin protein ligase.
    
 
 0.961
PTPN11
Protein tyrosine phosphatase non-receptor type 11.
    
   0.957
ENSCAPP00000013812
annotation not available
    
 0.956
SLC2A1
Solute carrier family 2 member 1.
    
 
 0.944
HDAC1
Histone deacetylase 1.
    
 
 0.918
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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