Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CGRRF1Cell growth regulator with ring finger domain 1. (332 aa)    
Predicted Functional Partners:
CGREF1
Cell growth regulator with EF-hand domain 1.
      
 0.858
RNF130
Ring finger protein 130.
     
 0.702
RNF145
Ring finger protein 145.
    
 
 0.701
ANKLE2
Ankyrin repeat and LEM domain containing 2.
    
 
 0.693
RNF19B
Ring finger protein 19B.
    
 0.669
RNF170
Ring finger protein 170.
      
 0.620
SEL1L
SEL1L adaptor subunit of ERAD E3 ubiquitin ligase.
      
 0.619
RNF121
Ring finger protein 121.
      
 0.570
RNF185
Ring finger protein 185.
      
 0.568
RNF5
Ring finger protein 5.
      
 0.568
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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