ISG15 protein (Cavia aperea) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

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experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

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[Homology]

Score

ISG15

ISG15 ubiquitin like modifier. (157 aa)

Predicted Functional Partners:

UBA7

0.999

UBE2L6

0.998

IRF9

0.996

ENSCAPP00000013767

0.996

DDX58

0.994

IFIH1

0.991

UBA1

0.987

ENSCAPP00000011344

0.987

ENSCAPP00000003297

0.985

ENSCAPP00000016515

0.985

Your Current Organism:

Cavia aperea

NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DDX58	ENSCAPP00000013767	ENSCAPP00000005483	ENSCAPP00000013767	DExD/H-box helicase 58.	annotation not available	0.948
DDX58	ENSCAPP00000016515	ENSCAPP00000005483	ENSCAPP00000016515	DExD/H-box helicase 58.	annotation not available	0.973
DDX58	IFIH1	ENSCAPP00000005483	ENSCAPP00000007628	DExD/H-box helicase 58.	Interferon induced with helicase C domain 1.	0.963
DDX58	IRF9	ENSCAPP00000005483	ENSCAPP00000009200	DExD/H-box helicase 58.	Interferon regulatory factor 9.	0.743
DDX58	ISG15	ENSCAPP00000005483	ENSCAPP00000004942	DExD/H-box helicase 58.	ISG15 ubiquitin like modifier.	0.994
DDX58	UBA1	ENSCAPP00000005483	ENSCAPP00000000539	DExD/H-box helicase 58.	Ubiquitin like modifier activating enzyme 1.	0.558
DDX58	UBA7	ENSCAPP00000005483	ENSCAPP00000014274	DExD/H-box helicase 58.	Ubiquitin like modifier activating enzyme 7.	0.589
DDX58	UBE2L6	ENSCAPP00000005483	ENSCAPP00000004102	DExD/H-box helicase 58.	Ubiquitin conjugating enzyme E2 L6.	0.781
ENSCAPP00000003297	ISG15	ENSCAPP00000003297	ENSCAPP00000004942	annotation not available	ISG15 ubiquitin like modifier.	0.985
ENSCAPP00000003297	UBE2L6	ENSCAPP00000003297	ENSCAPP00000004102	annotation not available	Ubiquitin conjugating enzyme E2 L6.	0.502
ENSCAPP00000011344	ISG15	ENSCAPP00000011344	ENSCAPP00000004942	annotation not available	ISG15 ubiquitin like modifier.	0.987
ENSCAPP00000011344	UBA1	ENSCAPP00000011344	ENSCAPP00000000539	annotation not available	Ubiquitin like modifier activating enzyme 1.	0.568
ENSCAPP00000011344	UBA7	ENSCAPP00000011344	ENSCAPP00000014274	annotation not available	Ubiquitin like modifier activating enzyme 7.	0.552
ENSCAPP00000011344	UBE2L6	ENSCAPP00000011344	ENSCAPP00000004102	annotation not available	Ubiquitin conjugating enzyme E2 L6.	0.632
ENSCAPP00000013767	DDX58	ENSCAPP00000013767	ENSCAPP00000005483	annotation not available	DExD/H-box helicase 58.	0.948
ENSCAPP00000013767	ENSCAPP00000016515	ENSCAPP00000013767	ENSCAPP00000016515	annotation not available	annotation not available	0.863
ENSCAPP00000013767	IFIH1	ENSCAPP00000013767	ENSCAPP00000007628	annotation not available	Interferon induced with helicase C domain 1.	0.880
ENSCAPP00000013767	IRF9	ENSCAPP00000013767	ENSCAPP00000009200	annotation not available	Interferon regulatory factor 9.	0.793
ENSCAPP00000013767	ISG15	ENSCAPP00000013767	ENSCAPP00000004942	annotation not available	ISG15 ubiquitin like modifier.	0.996
ENSCAPP00000013767	UBA1	ENSCAPP00000013767	ENSCAPP00000000539	annotation not available	Ubiquitin like modifier activating enzyme 1.	0.538