SFTPC protein (Cavia aperea) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

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[Homology]

Score

SFTPC

Surfactant protein C. (192 aa)

Predicted Functional Partners:

SFTPB

0.998

ENSCAPP00000001407

0.963

TMEM79

0.958

APP

0.923

P2RY2

0.916

ENSCAPP00000012569

0.908

CXCL9

0.890

FOXJ1

0.836

AQP5

0.780

ADRA2C

0.770

Your Current Organism:

Cavia aperea

NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADRA2C	SFTPB	ENSCAPP00000008992	ENSCAPP00000016575	Adrenoceptor alpha 2C.	Surfactant protein B.	0.647
ADRA2C	SFTPC	ENSCAPP00000008992	ENSCAPP00000004945	Adrenoceptor alpha 2C.	Surfactant protein C.	0.770
APP	ENSCAPP00000012569	ENSCAPP00000002952	ENSCAPP00000012569	Amyloid beta precursor protein.	annotation not available	0.597
APP	SFTPC	ENSCAPP00000002952	ENSCAPP00000004945	Amyloid beta precursor protein.	Surfactant protein C.	0.923
AQP5	SFTPB	ENSCAPP00000017916	ENSCAPP00000016575	Aquaporin 5.	Surfactant protein B.	0.603
AQP5	SFTPC	ENSCAPP00000017916	ENSCAPP00000004945	Aquaporin 5.	Surfactant protein C.	0.780
CXCL9	SFTPC	ENSCAPP00000007982	ENSCAPP00000004945	C-X-C motif chemokine ligand 9.	Surfactant protein C.	0.890
ENSCAPP00000001407	ENSCAPP00000012569	ENSCAPP00000001407	ENSCAPP00000012569	annotation not available	annotation not available	0.807
ENSCAPP00000001407	SFTPB	ENSCAPP00000001407	ENSCAPP00000016575	annotation not available	Surfactant protein B.	0.984
ENSCAPP00000001407	SFTPC	ENSCAPP00000001407	ENSCAPP00000004945	annotation not available	Surfactant protein C.	0.963
ENSCAPP00000012569	APP	ENSCAPP00000012569	ENSCAPP00000002952	annotation not available	Amyloid beta precursor protein.	0.597
ENSCAPP00000012569	ENSCAPP00000001407	ENSCAPP00000012569	ENSCAPP00000001407	annotation not available	annotation not available	0.807
ENSCAPP00000012569	SFTPB	ENSCAPP00000012569	ENSCAPP00000016575	annotation not available	Surfactant protein B.	0.826
ENSCAPP00000012569	SFTPC	ENSCAPP00000012569	ENSCAPP00000004945	annotation not available	Surfactant protein C.	0.908
FOXJ1	SFTPB	ENSCAPP00000013776	ENSCAPP00000016575	Forkhead box J1.	Surfactant protein B.	0.523
FOXJ1	SFTPC	ENSCAPP00000013776	ENSCAPP00000004945	Forkhead box J1.	Surfactant protein C.	0.836
P2RY2	SFTPB	ENSCAPP00000010728	ENSCAPP00000016575	Purinergic receptor P2Y2.	Surfactant protein B.	0.887
P2RY2	SFTPC	ENSCAPP00000010728	ENSCAPP00000004945	Purinergic receptor P2Y2.	Surfactant protein C.	0.916
SFTPB	ADRA2C	ENSCAPP00000016575	ENSCAPP00000008992	Surfactant protein B.	Adrenoceptor alpha 2C.	0.647
SFTPB	AQP5	ENSCAPP00000016575	ENSCAPP00000017916	Surfactant protein B.	Aquaporin 5.	0.603