Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSCAPP00000004969annotation not available (86 aa)    
Predicted Functional Partners:
SUFU
SUFU negative regulator of hedgehog signaling.
    
 0.955
CHRNA2
Cholinergic receptor nicotinic alpha 2 subunit.
      
 0.947
CHRNB4
Cholinergic receptor nicotinic beta 4 subunit.
      
 0.947
CHRNA10
Cholinergic receptor nicotinic alpha 10 subunit.
      
 0.945
CHRNA5
Cholinergic receptor nicotinic alpha 5 subunit.
      
 0.945
CCDC149
Coiled-coil domain containing 149.
      
 0.760
IQCA1
IQ motif containing with AAA domain 1.
      
 0.760
SLC36A1
Solute carrier family 36 member 1.
      
 0.747
ENSCAPP00000012574
annotation not available
      
 0.747
PRKACA
Protein kinase cAMP-activated catalytic subunit alpha.
    
  0.702
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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