IGFBP5 protein (Cavia aperea) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Gene Fusion

Cooccurrence

Coexpression

Experiments

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[Homology]

Score

IGFBP5

Insulin like growth factor binding protein 5. (159 aa)

Predicted Functional Partners:

IGFALS

0.972

ENSCAPP00000005171

0.951

PAPPA

0.938

IGF2

0.868

PAPPA2

0.772

IGF1

0.667

FAM20C

0.649

LGR5

0.574

MMP15

0.513

MMP14

0.513

Your Current Organism:

Cavia aperea

NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSCAPP00000005171	FAM20C	ENSCAPP00000005171	ENSCAPP00000010498	annotation not available	FAM20C golgi associated secretory pathway kinase.	0.611
ENSCAPP00000005171	IGF1	ENSCAPP00000005171	ENSCAPP00000011467	annotation not available	Insulin like growth factor 1.	0.819
ENSCAPP00000005171	IGF2	ENSCAPP00000005171	ENSCAPP00000001872	annotation not available	Insulin like growth factor 2.	0.916
ENSCAPP00000005171	IGFALS	ENSCAPP00000005171	ENSCAPP00000007074	annotation not available	Insulin like growth factor binding protein acid labile subunit.	0.994
ENSCAPP00000005171	IGFBP5	ENSCAPP00000005171	ENSCAPP00000004975	annotation not available	Insulin like growth factor binding protein 5.	0.951
ENSCAPP00000005171	LGR5	ENSCAPP00000005171	ENSCAPP00000016925	annotation not available	Leucine rich repeat containing G protein-coupled receptor 5.	0.423
ENSCAPP00000005171	PAPPA	ENSCAPP00000005171	ENSCAPP00000013939	annotation not available	Pappalysin 1.	0.455
FAM20C	ENSCAPP00000005171	ENSCAPP00000010498	ENSCAPP00000005171	FAM20C golgi associated secretory pathway kinase.	annotation not available	0.611
FAM20C	IGFBP5	ENSCAPP00000010498	ENSCAPP00000004975	FAM20C golgi associated secretory pathway kinase.	Insulin like growth factor binding protein 5.	0.649
IGF1	ENSCAPP00000005171	ENSCAPP00000011467	ENSCAPP00000005171	Insulin like growth factor 1.	annotation not available	0.819
IGF1	IGFBP5	ENSCAPP00000011467	ENSCAPP00000004975	Insulin like growth factor 1.	Insulin like growth factor binding protein 5.	0.667
IGF2	ENSCAPP00000005171	ENSCAPP00000001872	ENSCAPP00000005171	Insulin like growth factor 2.	annotation not available	0.916
IGF2	IGFALS	ENSCAPP00000001872	ENSCAPP00000007074	Insulin like growth factor 2.	Insulin like growth factor binding protein acid labile subunit.	0.619
IGF2	IGFBP5	ENSCAPP00000001872	ENSCAPP00000004975	Insulin like growth factor 2.	Insulin like growth factor binding protein 5.	0.868
IGF2	PAPPA	ENSCAPP00000001872	ENSCAPP00000013939	Insulin like growth factor 2.	Pappalysin 1.	0.578
IGF2	PAPPA2	ENSCAPP00000001872	ENSCAPP00000003125	Insulin like growth factor 2.	Pappalysin 2.	0.558
IGFALS	ENSCAPP00000005171	ENSCAPP00000007074	ENSCAPP00000005171	Insulin like growth factor binding protein acid labile subunit.	annotation not available	0.994
IGFALS	IGF2	ENSCAPP00000007074	ENSCAPP00000001872	Insulin like growth factor binding protein acid labile subunit.	Insulin like growth factor 2.	0.619
IGFALS	IGFBP5	ENSCAPP00000007074	ENSCAPP00000004975	Insulin like growth factor binding protein acid labile subunit.	Insulin like growth factor binding protein 5.	0.972
IGFBP5	ENSCAPP00000005171	ENSCAPP00000004975	ENSCAPP00000005171	Insulin like growth factor binding protein 5.	annotation not available	0.951