Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DENND6ADENN domain containing 6A. (379 aa)    
Predicted Functional Partners:
DENND11
DENN domain containing 11.
      
 0.752
DENND10
DENN domain containing 10.
      
 0.750
AVL9
AVL9 cell migration associated.
      
 0.742
PRKCSH
Protein kinase C substrate 80K-H.
    
   0.718
ENSCAPP00000008456
annotation not available
    
 
 0.710
LMTK2
Lemur tyrosine kinase 2.
    
   0.677
ARL15
ADP ribosylation factor like GTPase 15.
     
  0.675
DENND4C
DENN domain containing 4C.
      
 0.573
DENND1A
DENN domain containing 1A.
      
 0.567
CAMSAP2
Calmodulin regulated spectrin associated protein family member 2.
      
 0.562
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.