CLDN8 protein (Cavia aperea) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

CLDN8

Claudin 8. (225 aa)

Predicted Functional Partners:

CLDN16

0.963

TJP1

0.962

CLDN12

0.959

CLDN10

0.941

ENSCAPP00000006814

0.927

ENSCAPP00000015559

0.927

CLDN4

0.923

CLDN15

0.918

CLDN11

0.915

CLDN18

0.914

Your Current Organism:

Cavia aperea

NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea

Export your current network:

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TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CLDN10	CLDN11	ENSCAPP00000008489	ENSCAPP00000005577	Claudin 10.	Claudin 11.	0.912
CLDN10	CLDN12	ENSCAPP00000008489	ENSCAPP00000011062	Claudin 10.	Claudin 12.	0.959
CLDN10	CLDN15	ENSCAPP00000008489	ENSCAPP00000017038	Claudin 10.	Claudin 15.	0.911
CLDN10	CLDN16	ENSCAPP00000008489	ENSCAPP00000013197	Claudin 10.	Claudin 16.	0.933
CLDN10	CLDN18	ENSCAPP00000008489	ENSCAPP00000008887	Claudin 10.	Claudin 18.	0.919
CLDN10	CLDN4	ENSCAPP00000008489	ENSCAPP00000002742	Claudin 10.	Claudin 4.	0.911
CLDN10	CLDN8	ENSCAPP00000008489	ENSCAPP00000004992	Claudin 10.	Claudin 8.	0.941
CLDN10	ENSCAPP00000006814	ENSCAPP00000008489	ENSCAPP00000006814	Claudin 10.	annotation not available	0.939
CLDN10	ENSCAPP00000015559	ENSCAPP00000008489	ENSCAPP00000015559	Claudin 10.	annotation not available	0.939
CLDN10	TJP1	ENSCAPP00000008489	ENSCAPP00000009772	Claudin 10.	Tight junction protein 1.	0.943
CLDN11	CLDN10	ENSCAPP00000005577	ENSCAPP00000008489	Claudin 11.	Claudin 10.	0.912
CLDN11	CLDN12	ENSCAPP00000005577	ENSCAPP00000011062	Claudin 11.	Claudin 12.	0.957
CLDN11	CLDN15	ENSCAPP00000005577	ENSCAPP00000017038	Claudin 11.	Claudin 15.	0.911
CLDN11	CLDN16	ENSCAPP00000005577	ENSCAPP00000013197	Claudin 11.	Claudin 16.	0.914
CLDN11	CLDN18	ENSCAPP00000005577	ENSCAPP00000008887	Claudin 11.	Claudin 18.	0.912
CLDN11	CLDN4	ENSCAPP00000005577	ENSCAPP00000002742	Claudin 11.	Claudin 4.	0.924
CLDN11	CLDN8	ENSCAPP00000005577	ENSCAPP00000004992	Claudin 11.	Claudin 8.	0.915
CLDN11	ENSCAPP00000006814	ENSCAPP00000005577	ENSCAPP00000006814	Claudin 11.	annotation not available	0.934
CLDN11	ENSCAPP00000015559	ENSCAPP00000005577	ENSCAPP00000015559	Claudin 11.	annotation not available	0.934
CLDN11	TJP1	ENSCAPP00000005577	ENSCAPP00000009772	Claudin 11.	Tight junction protein 1.	0.947