STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SOCS5Suppressor of cytokine signaling 5. (536 aa)    
Predicted Functional Partners:
SOCS3
Suppressor of cytokine signaling 3.
     
 0.913
PIK3R5
Phosphoinositide-3-kinase regulatory subunit 5.
  
 
 0.907
ENSCAPP00000016562
annotation not available
    
 0.904
JAK1
Janus kinase 1.
    
 0.903
PIK3CA
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha.
   
 
 0.892
TYK2
Tyrosine kinase 2.
    
 0.890
JAK3
Janus kinase 3.
    
 0.890
JAK2
Janus kinase 2.
    
 0.890
STAT1
Signal transducer and activator of transcription 1.
    
 0.890
STAT3
Signal transducer and activator of transcription 3.
    
 0.887
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.