PARP3 protein (Cavia aperea) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

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Experiments

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[Homology]

Score

PARP3

poly(ADP-ribose) polymerase family member 3. (511 aa)

Predicted Functional Partners:

ENSCAPP00000009733

0.987

ENSCAPP00000012367

0.987

PARG

0.966

CASP9

0.938

ENSCAPP00000004580

0.938

ENSCAPP00000008032

0.938

ENSCAPP00000009599

0.912

XRCC6

0.852

RFC5

0.831

PCNA

0.830

Your Current Organism:

Cavia aperea

NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CASP9	ENSCAPP00000004580	ENSCAPP00000000581	ENSCAPP00000004580	Caspase 9.	annotation not available	0.993
CASP9	ENSCAPP00000008032	ENSCAPP00000000581	ENSCAPP00000008032	Caspase 9.	annotation not available	0.998
CASP9	ENSCAPP00000009733	ENSCAPP00000000581	ENSCAPP00000009733	Caspase 9.	annotation not available	0.952
CASP9	ENSCAPP00000012367	ENSCAPP00000000581	ENSCAPP00000012367	Caspase 9.	annotation not available	0.952
CASP9	PARP3	ENSCAPP00000000581	ENSCAPP00000005022	Caspase 9.	poly(ADP-ribose) polymerase family member 3.	0.938
CASP9	PCNA	ENSCAPP00000000581	ENSCAPP00000014064	Caspase 9.	Proliferating cell nuclear antigen.	0.560
ENSCAPP00000004580	CASP9	ENSCAPP00000004580	ENSCAPP00000000581	annotation not available	Caspase 9.	0.993
ENSCAPP00000004580	ENSCAPP00000008032	ENSCAPP00000004580	ENSCAPP00000008032	annotation not available	annotation not available	0.947
ENSCAPP00000004580	ENSCAPP00000009599	ENSCAPP00000004580	ENSCAPP00000009599	annotation not available	annotation not available	0.931
ENSCAPP00000004580	ENSCAPP00000009733	ENSCAPP00000004580	ENSCAPP00000009733	annotation not available	annotation not available	0.991
ENSCAPP00000004580	ENSCAPP00000012367	ENSCAPP00000004580	ENSCAPP00000012367	annotation not available	annotation not available	0.991
ENSCAPP00000004580	PARP3	ENSCAPP00000004580	ENSCAPP00000005022	annotation not available	poly(ADP-ribose) polymerase family member 3.	0.938
ENSCAPP00000004580	PCNA	ENSCAPP00000004580	ENSCAPP00000014064	annotation not available	Proliferating cell nuclear antigen.	0.516
ENSCAPP00000008032	CASP9	ENSCAPP00000008032	ENSCAPP00000000581	annotation not available	Caspase 9.	0.998
ENSCAPP00000008032	ENSCAPP00000004580	ENSCAPP00000008032	ENSCAPP00000004580	annotation not available	annotation not available	0.947
ENSCAPP00000008032	ENSCAPP00000009599	ENSCAPP00000008032	ENSCAPP00000009599	annotation not available	annotation not available	0.983
ENSCAPP00000008032	ENSCAPP00000009733	ENSCAPP00000008032	ENSCAPP00000009733	annotation not available	annotation not available	0.995
ENSCAPP00000008032	ENSCAPP00000012367	ENSCAPP00000008032	ENSCAPP00000012367	annotation not available	annotation not available	0.995
ENSCAPP00000008032	PARP3	ENSCAPP00000008032	ENSCAPP00000005022	annotation not available	poly(ADP-ribose) polymerase family member 3.	0.938
ENSCAPP00000008032	PCNA	ENSCAPP00000008032	ENSCAPP00000014064	annotation not available	Proliferating cell nuclear antigen.	0.726