STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IKZF2IKAROS family zinc finger 2. (512 aa)    
Predicted Functional Partners:
CRBN
Cereblon.
    
 
 0.642
RAD21L1
RAD21 cohesin complex component like 1.
    
 0.625
RAD21
RAD21 cohesin complex component.
    
 0.625
IKZF1
IKAROS family zinc finger 1.
   
  
0.613
DDB1
Damage specific DNA binding protein 1.
    
 0.607
SUFU
SUFU negative regulator of hedgehog signaling.
   
 0.568
IKZF3
IKAROS family zinc finger 3.
   
  
0.566
MYSM1
Myb like, SWIRM and MPN domains 1.
    
 0.562
CDK1
Cyclin dependent kinase 1.
    
  0.552
KDM6B
Lysine demethylase 6B.
    
 0.552
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.