Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
FAHFumarylacetoacetate hydrolase. (400 aa)    
Predicted Functional Partners:
EXO1
Exonuclease 1.
   
   0.957
HPD
4-hydroxyphenylpyruvate dioxygenase.
 
  
 0.951
ENSCAPP00000000571
annotation not available
  
 
  0.931
FH
Fumarate hydratase.
  
 0.929
RAG2
Recombination activating 2.
      
 0.925
SDHB
Succinate dehydrogenase complex iron sulfur subunit B.
  
 
  0.924
ENSCAPP00000006226
annotation not available
     
  0.911
FAHD2A
Fumarylacetoacetate hydrolase domain containing 2A.
     
 0.905
PLAU
Plasminogen activator, urokinase.
      
 0.879
ALB
Albumin.
      
 0.870
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
Server load: medium (62%) [HD]