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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPCS2Signal peptidase complex subunit 2. (123 aa)    
Predicted Functional Partners:
SPCS3
Signal peptidase complex subunit 3.
   
 0.998
SEC11C
SEC11 homolog C, signal peptidase complex subunit.
   
 0.989
ENSCAPP00000018588
annotation not available
   
 0.989
ITFG2
Integrin alpha FG-GAP repeat containing 2.
   
 0.870
XRCC4
X-ray repair cross complementing 4.
   
 0.870
IMMP2L
Inner mitochondrial membrane peptidase subunit 2.
   
 0.870
IMMP1L
Inner mitochondrial membrane peptidase subunit 1.
   
 0.870
HSPA5
Heat shock protein family A (Hsp70) member 5.
   
 
 0.793
SEC63
SEC63 homolog, protein translocation regulator.
    
 
 0.746
DDOST
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit.
   
 0.744
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.