Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
NFU1NFU1 iron-sulfur cluster scaffold. (236 aa)    
Predicted Functional Partners:
ENSCAPP00000010350
annotation not available
  
 0.992
ISCU
Iron-sulfur cluster assembly enzyme.
  
 0.975
ENSCAPP00000008637
annotation not available
  
 0.958
SDHB
Succinate dehydrogenase complex iron sulfur subunit B.
  
 
 0.949
ENSCAPP00000002569
annotation not available
  
 0.932
ENSCAPP00000009625
annotation not available
  
 0.932
SCLY
Selenocysteine lyase.
  
 0.928
FXN
Frataxin.
   
 
 0.898
ENSCAPP00000017570
annotation not available
  
 
 0.889
ENSCAPP00000010034
annotation not available
    
 0.880
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
Server load: medium (44%) [HD]