Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
IL12BInterleukin 12B. (321 aa)    
Predicted Functional Partners:
TYK2
Tyrosine kinase 2.
     
  0.843
JAK2
Janus kinase 2.
     
  0.843
IL6ST
Interleukin 6 signal transducer.
     
  0.798
IL7R
Interleukin 7 receptor.
   
 
  0.685
ENSCAPP00000001270
annotation not available
     
  0.678
UBTD1
Ubiquitin domain containing 1.
     
  0.678
IL2RB
Interleukin 2 receptor subunit beta.
     
  0.678
UBTD2
Ubiquitin domain containing 2.
     
  0.678
EPOR
Erythropoietin receptor.
     
  0.678
ENSCAPP00000004792
annotation not available
     
  0.677
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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