Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ARHGEF16Rho guanine nucleotide exchange factor 16. (699 aa)    
Predicted Functional Partners:
MAGI2
Membrane associated guanylate kinase, WW and PDZ domain containing 2.
    
   0.910
DOCK9
Dedicator of cytokinesis 9.
     
 0.863
ENSCAPP00000015831
annotation not available
     
 0.823
RHOG
Ras homolog family member G.
    
 0.800
EPHA8
EPH receptor A8.
    
 0.717
EPHB6
EPH receptor B6.
    
  0.713
ENSCAPP00000000853
annotation not available
    
 0.699
MYO9B
Myosin IXB.
      
 0.688
ECT2
Epithelial cell transforming 2.
     
 0.682
EPHA2
EPH receptor A2.
    
 0.676
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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