STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RAPGEF1Rap guanine nucleotide exchange factor 1. (1210 aa)    
Predicted Functional Partners:
CRKL
CRK like proto-oncogene, adaptor protein.
    
 0.990
CRK
CRK proto-oncogene, adaptor protein.
    
 0.983
ENSCAPP00000013675
annotation not available
    
 0.941
GRB2
Growth factor receptor bound protein 2.
   
 0.922
ENSCAPP00000015905
annotation not available
    
 0.918
RHOQ
Ras homolog family member Q.
    
 0.918
CBLB
Cbl proto-oncogene B.
    
 0.902
BCAR1
BCAR1 scaffold protein, Cas family member.
    
 0.886
ENSCAPP00000008920
annotation not available
    
 0.835
RHOJ
Ras homolog family member J.
    
 0.824
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.