Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TMEM259Transmembrane protein 259. (426 aa)    
Predicted Functional Partners:
TMUB1
Transmembrane and ubiquitin like domain containing 1.
    
 
 0.894
CACHD1
Cache domain containing 1.
      
 0.889
TMUB2
Transmembrane and ubiquitin like domain containing 2.
    
 
 0.874
RNF185
Ring finger protein 185.
    
 
 0.848
RNF5
Ring finger protein 5.
    
 
 0.848
STT3A
STT3 oligosaccharyltransferase complex catalytic subunit A.
      
 0.750
ENSCAPP00000016386
annotation not available
      
 0.744
GGCX
Gamma-glutamyl carboxylase.
      
 0.741
SMPDL3B
Sphingomyelin phosphodiesterase acid like 3B.
      
 0.728
EMC1
ER membrane protein complex subunit 1.
      
 0.694
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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