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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSCAPP00000005187annotation not available (184 aa)    
Predicted Functional Partners:
ENSCAPP00000015824
annotation not available
    
 0.956
RAPGEF4
Rap guanine nucleotide exchange factor 4.
    
 0.940
RASGRP2
RAS guanyl releasing protein 2.
    
 0.923
ITSN2
Intersectin 2.
    
 0.919
RAP1GAP
RAP1 GTPase activating protein.
    
 0.912
APBB1IP
Amyloid beta precursor protein binding family B member 1 interacting protein.
    
 0.908
ARAF
A-Raf proto-oncogene, serine/threonine kinase.
   
 0.901
RAF1
Raf-1 proto-oncogene, serine/threonine kinase.
   
 0.901
RASGRP3
RAS guanyl releasing protein 3.
    
 0.896
PRKACA
Protein kinase cAMP-activated catalytic subunit alpha.
    
 0.863
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.