Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
COTL1Coactosin like F-actin binding protein 1. (73 aa)    
Predicted Functional Partners:
ALOX12B
Arachidonate 12-lipoxygenase, 12R type.
    
 
 0.956
ALOX15B
Arachidonate 15-lipoxygenase type B.
    
 
 0.956
CAPZB
Capping actin protein of muscle Z-line subunit beta.
   
 0.847
ACTR2
Actin related protein 2.
   
 
 0.787
LCP1
Lymphocyte cytosolic protein 1.
   
 
 0.729
GPR17
G protein-coupled receptor 17.
      
 0.722
PLS1
Plastin 1.
   
 
 0.713
ENSCAPP00000004593
annotation not available
   
 
 0.703
CAP2
Cyclase associated actin cytoskeleton regulatory protein 2.
   
 
 0.703
IMMT
Inner membrane mitochondrial protein.
    
 0.688
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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