Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SLC45A2Solute carrier family 45 member 2. (472 aa)    
Predicted Functional Partners:
SLC24A5
Solute carrier family 24 member 5.
   
  
 0.950
OCA2
OCA2 melanosomal transmembrane protein.
      
 0.889
TYR
Tyrosinase.
   
 
 0.813
CORIN
Corin, serine peptidase.
      
 0.805
ENSCAPP00000001108
annotation not available
   
  
 0.746
MC1R
Melanocortin 1 receptor.
   
  
 0.692
DCT
Dopachrome tautomerase.
   
 
 0.674
ENSCAPP00000003704
annotation not available
   
  
 0.628
SLC24A4
Solute carrier family 24 member 4.
   
  
 0.622
GRIK5
Glutamate ionotropic receptor kainate type subunit 5.
   
 
 0.613
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
Server load: low (18%) [HD]