Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PLEKHM2Pleckstrin homology and RUN domain containing M2. (966 aa)    
Predicted Functional Partners:
KLC3
Kinesin light chain 3.
    
  0.917
KLC1
Kinesin light chain 1.
    
  0.917
KLC2
Kinesin light chain 2.
    
  0.917
KLC4
Kinesin light chain 4.
    
  0.917
KIF5B
Kinesin family member 5B.
     
  0.911
RAB9A
RAB9A, member RAS oncogene family.
     
  0.911
ENSCAPP00000010449
annotation not available
     
  0.911
KIF5A
Kinesin family member 5A.
     
  0.911
RAD23A
RAD23 homolog A, nucleotide excision repair protein.
   
 
 0.904
ENSCAPP00000016835
annotation not available
   
 
 0.882
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
Server load: low (18%) [HD]