Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ARAFA-Raf proto-oncogene, serine/threonine kinase. (569 aa)    
Predicted Functional Partners:
BRAF
B-Raf proto-oncogene, serine/threonine kinase.
   
 0.990
MAP2K1
Mitogen-activated protein kinase kinase 1.
   
 0.988
SHOC2
SHOC2 leucine rich repeat scaffold protein.
    
 0.984
ENSCAPP00000002279
annotation not available
   
 0.981
YWHAG
Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma.
    
 0.981
YWHAB
Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta.
    
 0.980
HRAS
HRas proto-oncogene, GTPase.
    
 0.979
AKT1
AKT serine/threonine kinase 1.
   
 0.979
YWHAZ
Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta.
    
 0.979
ENSCAPP00000015905
annotation not available
    
 0.978
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.