Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TYRO3TYRO3 protein tyrosine kinase. (831 aa)    
Predicted Functional Partners:
GAS6
Growth arrest specific 6.
    
 0.997
ENSCAPP00000016895
annotation not available
    
 0.968
ELMO1
Engulfment and cell motility 1.
    
 0.929
ADAM17
ADAM metallopeptidase domain 17.
    
 0.884
ENSCAPP00000011508
annotation not available
    
 0.866
ENSCAPP00000013205
annotation not available
    
 0.866
ADAM10
ADAM metallopeptidase domain 10.
    
 0.865
GAB1
GRB2 associated binding protein 1.
    
 0.865
ELMO3
Engulfment and cell motility 3.
    
 0.840
ELMO2
Engulfment and cell motility 2.
    
 0.840
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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