Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CYLDCYLD lysine 63 deubiquitinase. (854 aa)    
Predicted Functional Partners:
RIPK1
Receptor interacting serine/threonine kinase 1.
    
 0.998
TRAF6
TNF receptor associated factor 6.
    
 0.998
IKBKE
Inhibitor of nuclear factor kappa B kinase subunit epsilon.
    
 0.995
SQSTM1
Sequestosome 1.
    
 0.995
TRAF2
TNF receptor associated factor 2.
    
 0.994
BCL3
BCL3 transcription coactivator.
   
 0.992
TBK1
TANK binding kinase 1.
    
 0.991
ENSCAPP00000015425
annotation not available
    
 0.989
TNF
Tumor necrosis factor.
    
 0.987
ENSCAPP00000013360
annotation not available
    
 0.984
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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