STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RALGPS1Ral GEF with PH domain and SH3 binding motif 1. (578 aa)    
Predicted Functional Partners:
GRB2
Growth factor receptor bound protein 2.
    
 0.846
ENSCAPP00000008920
annotation not available
    
 0.749
ITSN2
Intersectin 2.
    
 0.742
PTPN6
Protein tyrosine phosphatase non-receptor type 6.
    
 0.708
PTPN11
Protein tyrosine phosphatase non-receptor type 11.
    
 0.708
LRRC7
Leucine rich repeat containing 7.
    
 0.674
ABLIM2
Actin binding LIM protein family member 2.
      
 0.659
SHC3
SHC adaptor protein 3.
    
 0.657
SHC1
SHC adaptor protein 1.
    
 0.657
PRKACA
Protein kinase cAMP-activated catalytic subunit alpha.
    
 0.653
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
Server load: low (14%) [HD]