Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
KLHL28Kelch like family member 28. (544 aa)    
Predicted Functional Partners:
IPP
Intracisternal A particle-promoted polypeptide.
    
  0.949
KLHL24
Kelch like family member 24.
   
   0.923
ENSCAPP00000001389
annotation not available
    
 0.920
CUL3
Cullin 3.
    
 0.915
KLHL26
Kelch like family member 26.
    
  0.912
NUDCD3
NudC domain containing 3.
    
 
 0.872
ENSCAPP00000008727
annotation not available
    
  0.864
KLHL12
Kelch like family member 12.
    
  0.847
KEAP1
Kelch like ECH associated protein 1.
    
   0.811
RNF166
Ring finger protein 166.
    
 
 0.760
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
Server load: low (12%) [HD]